李鹏成
李鹏成,博士,副研究员,江苏省农业科学院动物免疫工程研究所免疫技术研究室骨干。
 
一、主要研究方向
1.猪重大疫病新型疫苗研究;2.益生菌对病原菌拮抗机制研究
二、主要承担课题
1.主持国家自然基金项目“乳酸杆菌S-层蛋白拮抗PEDV感染宿主细胞机制的研究”(编号3111529)
2.主持江苏省农业自主创新资金项目“GEM系统抗原展示技术研究”(编号:511262)。
三、主要科研成果
 (一)代表论文 
1. Pengcheng Li, Xuwen Qiao, Qisheng Zheng, Jibo Hou. Immunogenicity and immunoprotection of porcine circovirus type 2 (PCV2) Cap protein displayed by Lactococcus lactis. Vaccine. 2016 34(5):696-702.
2. Pengcheng Li, Yunfeng Li, Guoqing Shao, Qinghua Yu Qian Yang. Comparison of immune responses to intranasal and intrapulmonary vaccinations with the attenuated Mycoplasma hyopneumoniae 168 strain in pigs. J. Vet. Med. Sci. 2015, 77(5): 519–525.
3. Pengcheng Li, Yinyan Yin, Qinghua Yu, Qian Yang. Lactobacillus acidophilus S-layer protein-mediated inhibition of Salmonella-induced apoptosis in Caco-2 cells. Biochem Biophys Res Commun, 2011, 409: 142-147.
4. Pengcheng Li, Qinghua Yu, Xiaolan Ye, Zhisheng Wang, Qian Yang. Lactobacillus S-layer proteins inhibition of Salmonella-induced reorganization of F-actin and activation of MAPK signaling pathways in Caco-2 cells. Microbiology, 2011, 157: 2639-2646.
5. Pengcheng Li, Xiaolan Ye, Qian Yang. Antagonistic activity of Lactobacillus acidophilus S-layer proteins on Salmonella Typhimurium in Caco-2 cells. Ann Microbiol, 2011, doi: 10.1007/s13213-011-0327-1.
6. Qinghua Yu, Pengcheng Li, Qian Yang. Improving the absorption of earthworm fibrinolytic enzymes with mucosal enhancers. Pharmaceutical Biology, 2010, 48(7): 816–821.
7. Yunfeng Li, Pengcheng Li, Xueping Wang, Qinghua Yu, Qian Yang. Co-administration of attenuated Mycoplasma hyopneumoniae 168 strain with bacterial DNA enhances the local and systemic immune response after intranasal vaccination in pigs. Vaccine, 2012, 30(12):2153-2158.
8. 李鹏成,孙冰,乔绪稳,郑其升,侯继波. 乳酸乳球菌肽聚糖锚钩蛋白原核表达载体的构建与表达. 江苏农业学报,2013, 29(6):1399-1404.
9. 李鹏成,刘志学,高君恺,庾庆华,杨倩. 猪呼吸道IgA和IgG分泌细胞分布研究. 畜牧兽医学报,2010, 41(7): 873-877.
10. 李鹏成,叶小兰,王志胜,庾庆华,杨倩. 乳酸杆菌S-层蛋白对鼠伤寒沙门氏菌黏附及入侵Caco-2细胞的拮抗作用. 微生物学报,2010, 50(9): 1226-1231.
11. 李鹏成,庾庆华,杨倩. 口蹄疫灭活病毒鼻腔免疫对猪免疫应答的影响. 中国兽医科学,2009.
(二)授权专利:
  1.编码重组猪圆环病毒2型Cap蛋白的基因及其应用,201310065186.4,第1完成人。